Detalhe da pesquisa
1.
Processing Temporal Growth Factor Patterns by an Epidermal Growth Factor Receptor Network Dynamically Established in Space.
Annu Rev Cell Dev Biol
; 36: 359-383, 2020 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32692593
2.
The interdependence of membrane shape and cellular signal processing.
Cell
; 156(6): 1132-1138, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24630717
3.
KRas localizes to the plasma membrane by spatial cycles of solubilization, trapping and vesicular transport.
Cell
; 157(2): 459-471, 2014 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24725411
4.
Signaling from the living plasma membrane.
Cell
; 144(6): 897-909, 2011 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21414482
5.
The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins.
Cell
; 141(3): 458-71, 2010 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20416930
6.
Spatial organization of intracellular communication: insights from imaging.
Nat Rev Mol Cell Biol
; 11(6): 440-52, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20485292
7.
PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas.
Int J Cancer
; 144(4): 767-776, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30194764
8.
Reversible cryo-arrest for imaging molecules in living cells at high spatial resolution.
Nat Methods
; 13(8): 665-672, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27400419
9.
Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling.
Nature
; 497(7451): 638-42, 2013 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23698361
10.
Hypertonicity-induced cation channels in HepG2 cells: architecture and role in proliferation vs. apoptosis.
J Physiol
; 596(7): 1227-1241, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29369356
11.
miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL.
Blood
; 125(19): 2948-57, 2015 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25670628
12.
A PDE6δ-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2.
Angew Chem Int Ed Engl
; 56(9): 2423-2428, 2017 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28106325
13.
Direct Measurement of Water States in Cryopreserved Cells Reveals Tolerance toward Ice Crystallization.
Biophys J
; 110(4): 840-9, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26541066
14.
Adaptive responses of cell hydration to a low temperature arrest.
J Physiol
; 594(6): 1663-76, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26593308
15.
The Function of Embryonic Stem Cell-expressed RAS (E-RAS), a Unique RAS Family Member, Correlates with Its Additional Motifs and Its Structural Properties.
J Biol Chem
; 290(25): 15892-15903, 2015 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25940089
16.
The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins.
Biophys J
; 106(1): 93-105, 2014 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24411241
17.
Configurable low-cost plotter device for fabrication of multi-color sub-cellular scale microarrays.
Small
; 10(14): 2870-6, 2014 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24678019
18.
Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate.
Nat Cell Biol
; 9(3): 324-30, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17310240
19.
Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling.
Nat Cell Biol
; 9(11): 1319-26, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17952059
20.
Cell cycle-dependent binding modes of the ran exchange factor RCC1 to chromatin.
Biophys J
; 104(8): 1642-51, 2013 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23601311